From initial research to production and then to market launch, vaccines undergo strict quality control, with environmental parameter monitoring being one of the processes.

Rotronic temperature and humidity products have won a good reputation in the pharmaceutical industry for their performance, accumulating tens of thousands of customers worldwide, including industry leaders. In 2020, Rotronic was given priority in the field of vaccine development, providing temperature and humidity monitoring solutions for vaccine production and storage.

　　Project Overview:

Rotronic's partners in this vaccine project have 20 years of experience in vaccine development, dedicated to the research, production, and sales of human vaccines. Last year, they were also awarded the honorary title of National Advanced Collective in Fighting against the Pneumonia Epidemic. At the beginning of this year, the vaccine developed by this partner went international. The project owner is making every effort to upgrade production facilities and build a production base in order to launch better vaccines. The first phase of 500 million tubes has been completed and put into operation, which has not only passed the GMP acceptance of the State Food and Drug Administration, but also passed the GMP inspection of Brazil, Chile, Singapore, Türkiye and other countries.

The entire process of vaccine research and development, production, storage, and transportation needs to be carried out in a controlled environment. Whether temperature and humidity monitoring is in place, accurate, and stable directly affects the efficacy of the vaccine. If the storage temperature of the vaccine is between 2 ℃ and 8 ℃, and the temperature of the cold storage is set at a constant temperature of 5 ℃, if the temperature and humidity sensors have large measurement errors and unstable drift in such situations, it will have a significant impact on the efficacy of the vaccine. The monitoring values of temperature and humidity in vaccine laboratories, production workshops, quality control, materials and other links are different. Some require general temperature, some require low temperature, and some require ultra-low temperature. This requires a product series with "versatile" performance. In addition, there are requirements for installation flexibility.

　　Application plan:

In order to build a production base, the owner has put forward high standards for environmental measurement, among which achieving high-precision humidity measurement and high-precision ultra-low temperature measurement, compliance, and flexible arrangement of measurement points are the difficulties.

Rotronic temperature and humidity products have the characteristics of high measurement accuracy, long-term stability, more flexible digital settings and calibration, and adaptability to complex application environments, which have been unanimously recognized by project owners and integrators of construction projects. Rotronic temperature and humidity products are continuously used in multiple projects such as P3, QC, production workshops, material warehouses, animal laboratories, and formulations, providing precise and stable data for environmental control in vaccine research and development, production, and storage. The P3 laboratory, also known as the biosafety protection level three laboratory, is sealed and the indoor environment is under negative pressure, which poses higher requirements for the performance and installation of temperature and humidity sensors.

With the launch of the project, our products have been tested in different temperature and humidity control stages of vaccines, and it has been proven that they can well meet the strict requirements of environmental monitoring.

　　Application products:

The products applied in the entire project include the HF1 series of duct temperature and humidity sensors, the HF3 series of duct temperature/dew point sensors, the HF5 series of indoor temperature and humidity sensors, and the HC2A-S probe. These products are provided according to the different temperature and humidity requirements of the owner's application environment.

　　Product Introduction

HF1 series:

The measurement range is -20~50 ℃ for temperature and 0~100% RH for humidity;

The temperature accuracy is, with humidity<2% RH (10~90% RH) and temperature ± 0.3 ℃ 23 ℃± 5 ℃;

Hygrometer IN-1 humidity sensor;

Free configuration of voltage or current analog output;

USB service interface;

Small size, easy and convenient installation.

　HF3 series:

The measurement range is -40~60 ℃ for temperature and 0~-100% RH for humidity;

The measurement accuracy is ± 2% RH 23 ℃± 5 ℃, ± 0.2 ℃ 23 ℃± 5 ℃;

Two point temperature calibration, up to 100 points humidity digital calibration, ensuring long-term measurement accuracy;

Economical and durable, available in wall mounted/duct type;

Optional (H) humidity measurement accuracy ± 1.5% RH, sterilization resistant environment sensor (to be selected according to sterilization concentration, cycle, duration, and other conditions).

　　HF5 series:

Split type temperature and humidity sensor;

Optional with or without display, flexible configuration, multiple probe options available;

The measurement range depends on the probe (-50~100 ℃ and -100~100 ℃ in this project);

The accuracy depends on the probe (accuracy ± 0.15 ℃ 23 ℃± 5 ℃ in this project);

Two point digital calibration, fixed value analog function;

The 4-wire PT100 can eliminate errors caused by extension cords;

Optional extension cable length ensures accuracy while flexibly arranging sensor positions.

　HC2A-S probe:

The measurement range is -50~100 ℃ for temperature and 0~100% RH for humidity;

The temperature accuracy is ± 0.1 ℃ 23 ℃± 5 ℃, and the humidity is ± 0.8% RH 23 ℃± 5 ℃;

Provide two-point temperature calibration and up to 100 digital humidity calibration points to ensure long-term measurement accuracy;

Accurate repeatability;

Excellent long-term stability<1% RH/year.