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Peptide solid-phase synthesis device | combination set, one-step in place, meets experimental requirements
Date: 2025-08-14Read: 19

多肽固相合成装置|组合套装,一步到位,满足试验需求


Peptide solid-phase synthesis device is a specialized equipment used to perform the key chemical process of peptide solid-phase synthesis. It achieves gradual construction on a solid-phase carrier

The technology of building polypeptide chains. The device is fully automated and controlled throughout the entire process, equipped with a PLC control system that supports user input and editing of peptide synthesis sequences

Automatically execute the synthesis steps according to the preset sequence, and set reaction parameters.


多肽固相合成装置|组合套装,一步到位,满足试验需求


Product Features

1. The reaction kettle, mixing tank, and activation tank are made of 3.3 borosilicate glass or stainless steel 316L, and the kettle cover is made of PTFE or 316L. Top stirring is used;


多肽固相合成装置|组合套装,一步到位,满足试验需求


2. Support user input and editing of peptide synthesis sequences, capable of automatically executing synthesis steps according to preset sequences;


多肽固相合成装置|组合套装,一步到位,满足试验需求


3.Can set reaction parameters (temperature, time, stirring speed, liquid dosage);

4. The reaction temperature is between 0-70 ℃;
5. The filter plate of the reaction kettle is made of 316L or PE material, and the bottom can be filled with inert gas;

多肽固相合成装置|组合套装,一步到位,满足试验需求


6. The reaction kettle, mixing tank, and activation tank can all be protected with inert gas;
7. The accuracy error of liquid addition is ≤± 1%;
8. Real time recording of reaction parameters (temperature, pressure, stirring speed, flow rate), data can be exported
9. Overall dismantling design;
10. Explosion proof and non explosion proof products can be provided;
11. Explosion proof products are suitable for use in hazardous areas Zone 2, with explosive gases classified as IIB and explosive gas temperature group T4;
12. Customization can be made according to different processes;


Specifications

多肽固相合成装置|组合套装,一步到位,满足试验需求


Application of Peptide Solid Phase Synthesis Device

1.Drug development and production:

Therapeutic peptide drugs: synthetic insulin analogues, GLP-1 receptor agonists (such as semaglutide), antimicrobial peptides, hormone analogues, etc.
Peptide vaccine: Synthesize specific antigenic epitope peptides for vaccine development.
Drug discovery: Quickly synthesize a large peptide library for high-throughput screening, searching for lead compounds with biological activity (such as kinase inhibitors, receptor antagonists/agonists).

2. Diagnostic reagents:

Immunoassay: Synthesize peptides as antigens or haptens for the preparation of antibodies, which are used in diagnostic kits such as ELISA, immunoblotting, immunohistochemistry, etc.
Biomarker detection: Synthesize peptides that mimic disease-related protein epitopes for detecting specific antibodies in patient serum.


3. Basic research and biochemistry:

Protein Structure and Function Research: Synthesize specific fragments of proteins (domains, active site peptides), study their folding, interactions, and functions.
Enzymology: synthesis enzyme substrates, inhibitors, or transition state analogues.
Molecular Interaction Research: Synthesize peptide ligands for SPR, ITC, fluorescence polarization, and other technologies to study protein-protein and protein nucleic acid interactions.
Epitope localization: Synthesize overlapping peptide segments to accurately locate epitope regions recognized by antibodies or receptors.

4. Materials Science:

Biomaterials: synthesis of polypeptides with specific self-assembly properties, used to prepare nanofibers, hydrogels, etc., and used in tissue engineering and drug delivery.

Biosensing: Fixing functional peptides on the sensor surface for detecting specific molecules.


5. Cosmetics industry:

Synthesize signal peptides with specific biological activities (such as palmitoyl pentapeptide-4, acetyl hexapeptide-8) for cosmetics with anti-aging and collagen synthesis promoting effects.

6. Affinity purification:

Synthesize peptides containing specific tags (such as FLAG, HA, His tag) for immobilized metal affinity chromatography, immunoaffinity chromatography, or streptavidin purification systems.