Conventional Analysis High Performance Liquid Chromatography

Conventional Analysis High Performance Liquid Chromatography Product advantages

1. The combination of ellipsoidal mirror and concave grating optical system ensures the accuracy and sensitivity of test results with minimal aberration, chromatic aberration, and ultra-low stray light;

2. Dual light source structure of tungsten lamp and transmissive deuterium lamp - no need to replace the lamp, can achieve sample detection in the wavelength range of 190nm-800nm;

3. Series type dual plunger high-pressure infusion pump - using one-time molding dual cam drive technology, the phase difference between the main and auxiliary cams is constant, ensuring stable liquid flow during long-term operation;

4. Multi channel solvent organizer - adopting advanced semi permeable membrane negative pressure degassing method and timed plunger automatic cleaning technology, it can achieve online degassing of mobile phase and plunger cleaning;

5. Chinese and English chromatography workstation - compliant with GLP standards, capable of tracking the entire process of analysis methods, collection, and processing.

Conventional Analysis High Performance Liquid Chromatography

1. High sensitivity UV/visible detector

a) The combination of ellipsoidal mirror and concave grating optical system ensures the accuracy and sensitivity of test results with minimal aberration, chromatic aberration and ultra-low stray light;

b) The controllable temperature flow pool improves the stability of the baseline and ensures high reliability of the analysis results;

c) Built in large capacity data storage card, supports data storage during power outages, ensuring the security of your data;

d) Dual light source structure of tungsten lamp and transmissive deuterium lamp - no need to replace the lamp, can achieve sample detection in the wavelength range of 190nm-800nm;

2. Series double plunger high-pressure infusion pump

a) Adopting one-time molding dual cam drive technology, the phase difference between the main and auxiliary cams is constant, ensuring stable liquid flow during long-term operation;

b) By utilizing advanced solvent compressibility compensation technology and optimizing parameters, the pressure pulsation of the pump can be reduced to below 1%, providing you with a smoother liquid flow;

3. Multi channel solvent organizer - adopting advanced semi permeable membrane negative pressure degassing method and timed plunger automatic cleaning technology, it can achieve online degassing of mobile phase and plunger cleaning;

4. Automatic sampler

a) Flexible injection methods: full quantification, partial quantification, and portable injection mode;

b) Ultra high injection accuracy: full quantification (<0.3%), partial quantification (<0.5%), and portable injection mode (<1.0%);

c) Minimal injection residue: able to minimize injection contamination caused by highly adsorbed substances to the greatest extent possible;

d) Refrigerable injection chamber: Peltier cooling, temperature can be as low as 4 ℃.

5. Chinese and English chromatography workstations

a) User role management and GLP record planning laboratory management operations comply with the data reliability requirements of GMP appendices "Computerized Systems" and "Confirmation and Validation"

The combination of user management function and GLP function can not only prevent experimenters from improper operation of unfamiliar functions, causing instrument damage or performance degradation, but also record experimenters' operation steps and data analysis steps, providing reliable guarantee for experimenters' query and analysis.

On May 26, 2015, CFDA officially released the new appendices "Computerized Systems" and "Confirmation and Verification" of the 2010 version of GMP regulations. The regulatory requirements for computer system compliance can be summarized as follows: access control, permission allocation, audit trail, and electronic signature.

For pharmaceutical manufacturing enterprises, workstations have the functions of "access control, permission allocation, audit tracking, and electronic signature" to ensure that the product inspection process and data reliability of the enterprise meet regulatory requirements.

b) Design functions and processes that are close to user applications, making the user experience more immersive

1) Application analysis experts participate in research and development, and user experience from various industries is crystallized

The instrument control interface adheres to the consistent design style of Puxi General Software, with clear structural hierarchy and emphasis on functional practicality. Driven by the actual needs of users, application analysis experts are fully involved in guiding research and development, and a large number of domestic users engage in practical communication, fully analyzing users' usage habits. Integrating spectrum display, method editing, instrument parameters, and sequence control into one interface for easy switching, effectively expanding the screen's usable area. Effectively layout the analysis process and functional design according to usage frequency, making it easier for users to find commonly used operational functions.

2) Automated analysis process, batch processing of control, collection, analysis, and reporting to cope with a large number of analysis tasks

The software realizes the setting and control of various parameters of the instrument, as well as the simultaneous acquisition of multi-channel digital signals. The data acquisition process has the function of single and sequential automatic sampling. Record the frequency and duration of use of various consumables, and provide reminders for consumables with a lifespan exceeding the threshold. Data analysis can achieve batch data quantification and batch printing of reports, greatly improving the efficiency of experimental analysis.

c) Powerful integration, qualitative, and quantitative data analysis capabilities to meet diverse analysis needs

（1） Chromatographic methods - comprehensive qualitative and quantitative methods

Assist in chromatographic qualitative analysis through chromatographic knowledge base, qualitative table, and sample analogy function. Quantification includes various quantitative methods such as internal standard method, external standard method, normalization method, and calibration normalization method, as well as calibration curves with different fitting methods. Qualitative and quantitative detection can be carried out by quickly and accurately adjusting and optimizing chromatographic methods. At the same time, multiple data can be compared and operated on chromatograms, and RSD statistics of peak information and content can be performed with one click.

（2） Chromatography Integral Tool - Fast and Easy

The chromatographic integration tool can automatically identify chromatographic peaks and manually or automatically integrate target peaks. Manual integration includes various operations such as deleting peaks, adding peaks, valley segmentation, vertical segmentation, canceling integration, forcing peak splitting, forcing single peak, negative peak processing, etc. Set parameters such as peak height, peak area, threshold, and integration time as needed. Quick icons for various integration functions make the operation simple and the interface intuitive.

（3） Report printing function - WYSIWYG report design, diversified report functions

Seamless connection between data analysis and report printing has been achieved. Implement template preview and batch printing functions for data. The WYSIWYG report editing mode allows for automatic formatting of reports by selecting the desired content without the need for complex operations.

Technical Specifications