Large scale drug walk-in constant temperature and humidity laboratory

1Large scale drug walk-in constant temperature and humidity laboratoryTechnical feature: the cornerstone of accurately simulating environmental conditions

The walk-in drug stability laboratory meets the strict requirements of the pharmaceutical industry for environmental simulation with a flexible volume of 2m ³~300m ³, temperature control accuracy of ± 0.5 ℃, and humidity control accuracy of ± 2% RH. Its core advantages are reflected in:

Multi dimensional protection system: integrates power overload, phase loss, leakage protection, as well as compressor high/low voltage protection and over temperature protection devices to ensure stable operation of equipment.

Efficient refrigeration and heating humidification system: using original French Taikang fully enclosed compressor, Italian solenoid valve, and stainless steel heating components to achieve rapid temperature and humidity regulation and shorten the testing cycle.

Intelligent control system: The 7-inch true color large screen LCD touch screen supports multiple program settings and can simulate complex environments such as day night temperature differences and seasonal humidity changes, providing scientific basis for drug stability research.

2、 Application scenarios in the pharmaceutical industry: Quality control throughout the entire lifecycle

Drug development and stability research

Accelerated testing: Simulate the long-term storage environment of drugs under high temperature and high humidity conditions (such as 40 ℃± 2 ℃, 75% RH ± 5% RH), and predict the expiration date. For example, a biopharmaceutical company verified the degradation rate of a certain anti-cancer drug under temperature and humidity conditions through a test chamber, shortening the validity period prediction period from 3 years to 6 months.

Influencing factor experiment: Evaluate the impact of packaging materials on drug stability and optimize packaging design by controlling temperature (such as -20 ℃ to 60 ℃), humidity (such as 20% RH to 95% RH), and lighting conditions.

Production process validation

Optimization of freeze-drying process: Simulate the freeze-drying process within a wide temperature range of -50 ℃ to 80 ℃, and verify the water removal efficiency during the sublimation stage by combining humidity control to ensure the uniformity and stability of the freeze-dried formulation.

Sterilization process validation: Simulate wet and hot sterilization conditions through high temperature and high humidity (such as 121 ℃, 100% RH) to verify the uniformity of temperature distribution inside the sterilization cabinet and ensure the safety of sterile preparations.

Verification of storage and transportation conditions

Cold chain transportation simulation: In a low-temperature environment of 2 ℃ to 8 ℃, combined with humidity fluctuation testing, evaluate the stability of drugs during transportation and reduce quality risks caused by temperature and humidity control.

Long term storage test: Continuously monitor changes in the physicochemical properties of drugs under constant temperature and humidity conditions (such as 25 ℃± 2 ℃, 60% RH ± 5% RH) to provide data support for drug storage conditions.

3、 Technical specifications and parameters:

4、 Room structure:

The chamber adopts a combined storage plate structure, which can be easily assembled on the buyer's site

The indoor wall material of the laboratory is SUS304 stainless steel plate, and the outer wall material is high-quality cold-rolled steel plate. The outer surface is electrostatically painted with a light gray white color; 100mm polyurethane foam and high-density aluminum silicate insulation layer in the middle

The workshop floor is made of anti slip patterned steel plate, and the anti slip slope should ensure that the trolley can easily enter and exit the workshop

The laboratory adopts a double door structure, equipped with internal and external handles

Install moisture-proof lighting on the top of the workspace, with one cable lead out hole on each side (which can be sealed when not in use)

The structure of the laboratory should be designed reasonably, manufactured with excellent technology, aesthetically pleasing both inside and outside surfaces, and the stainless steel plates and electrostatic spraying surfaces should be smooth and free of defects such as bumps and scratches.

Studio size: customized according to requirements, with volumes ranging from 1m ³ to 200 cubic meters

5、 Refrigeration system

Refrigerator: Adopting French Taikang fully enclosed refrigeration compressor unit (or American valley wheel compressor)

Refrigeration method: To ensure the cooling rate and ability to reach extremely low temperatures required by the test chamber, the chamber adopts a stacked refrigeration method

The design of refrigeration systems should incorporate energy regulation technology, which is an effective way to ensure that the energy consumption and cooling capacity of the refrigeration system can be effectively adjusted while the refrigeration unit is operating normally, reducing the operating costs and failure rates of the refrigeration system to a more economical state.

Refrigeration auxiliary components: air-cooled coil condenser, finned multi-stage evaporator. The main refrigeration accessories and control components are imported, such as the American "Aigo" drying filter, the Italian "Castello" solenoid valve, etc;

Refrigerant: R404A is used

Cooling method: air cooling

Installation method: Split outdoor

6、 Heater: finned heat dissipation tube type nickel chromium alloy electric heating method

7、 Humidification system: External humidifier, water addition can be done automatically or manually

8Large scale drug walk-in constant temperature and humidity laboratoryControl system:

Controller: 7-inch true color LCD digital display programmable touch screen controller.

Controller specifications:

Accuracy: Temperature ± 0.1 ℃+1 digit

Resolution: Temperature ± 0.01

Temperature slope: adjustable from 0.1 to 9.9

Equipped with upper and lower limit standby and alarm functions

Temperature input force signal PT100

Screen display function:

Direct display of temperature setting (SV) and actual (PV) values

Can display the current program execution number, segment number, remaining time, and number of cycles

Accumulated operation time function

Has a separate program editing screen.

The screen display protection function can be set to timer, TIMER, or manually turned off

Program capacity and control functions:

Available program groups: A total of 120 PATTEN

Available memory capacity: 1200 SEGMENT in total

Repeatable command execution

SEGMENT time setting: 0-99Hour59Min

Equipped with power-off program memory, it automatically starts and continues to execute program functions after power restoration

Equipped with RS-232 communication interface and dedicated testing software (optional accessories)

Real time display of graphical curves during program execution

It has the function of scheduled startup and shutdown

Has date and time adjustment function

9、 Installation and debugging:

(1) Home delivery, complete system installation with quality and quantity as required by the contract, and our engineering and technical personnel conduct debugging.

(2) The product manual provides installation and interface information, which greatly facilitates equipment maintenance.

(3) Provide training for equipment users to enable them to operate the equipment independently in the future. Master the operation, daily maintenance, and simple repairs of the product.

10、 Warranty Commitment:

From the date of acceptance, a two-year warranty will be provided (except for damages caused by natural disasters, abnormal electricity, improper use, or improper maintenance, our company will provide free repairs).

For services beyond the warranty period, only corresponding cost fees will be charged.

Any problems that occur during the use of the equipment should be responded to within 24 hours, and maintenance engineers and technicians should be promptly dispatched to handle and solve the problems.

Promise to provide lifelong free technical support.