Operetta High Content System

With the deepening exploration of complex biological problems by scientists, the demand for large-scale and complex biological models by researchers is becoming increasingly widespread. So they chose Operetta CLS ® High connotation screening system - a tool for studying the internal mechanisms of healthy or diseased cells.

Operetta High Content System

Part number: HH12000000

Overview

Introducing the new generation Operetta CLS to you comprehensively ™ High connotation screening system

Whether you are conducting experimental design, whole genome siRNA screening, compound screening, or want to perform fine cell phenotype observation on some samples, or using 3D disease models, primary cells, liver cells, live cells, or weakly signal fixed cells, the Operetta high content screening system provides the solution you need for reliable consistency testing.

Even for primary candidates, they can quickly master high content screening and high content data analysis.

High content screening with good clarity

Fast and Wide Field Imaging for Common Applications

True hardware turntable confocal imaging can remove non focal plane signals and achieve low light toxicity and low light quenching in live cell imaging

Optimization design of pinhole size for a system objective lens using a rotating disc confocal microscope

The eight position dichroic mirror wheel provides excitation flexibility

Fully automatic high-throughput image acquisition and multi view hardware focusing compatible with glass slides and porous plates

Depth of Field Extended Imaging for Unlabeled Cell Detection and Data Analysis

High numerical aperture objective provides you with better image quality and more reliable data analysis

Intelligent scanning of low magnification and high magnification data helps you obtain full hole images while intelligently capturing highly interested fields of view

Various specifications of high content screening boards can provide one-stop assistance for your high content screening projects. At the same time, we also offer a variety of cell carrier ultra-low adsorption 3D microstructure boards suitable for high content screening, helping you establish a 3D cell screening model

Our local and global hardware and application technology support teams provide you with new applications developed by PerkinElmer Laboratory and professional experimental application support

Harmony high connotation data collection and analysis software brings you objective and reliable data analysis

Intelligent and user-friendly high connotation image acquisition and analysis software is designed and optimized using biological language, allowing researchers to easily obtain effective quantitative image data information

A team of R&D experts with years of experience in high content screening will continue to develop and upgrade software for your experiments

Simple, intuitive, and seamless experimental condition settings, experimental collection, image analysis, and data result evaluation and display

Guided porous plate registration interface - helps you easily register the new type of porous plate you need, with fully automatic detection functions for plate height and plate floor thickness

Pre designed application-oriented image analysis solution helps you start image analysis with just one click and generate experimental data

The flexible image analysis module provides free creation of analysis methods, making it easy for beginners to start creating, modifying, and defining high content analysis modules in the first place.

Advanced image analysis features such as STAR morphological analysis can assist you in conducting fine cell morphology analysis with multiple parameters and identifying and defining changes in cell phenotype

Cell texture calculation and analysis can provide you with three-dimensional data beyond fluorescence intensity and morphological information, providing you with quantitative analysis of cell phenotype changes that traditional quantitative methods cannot quantify

Seamless and meticulous complex data analysis modules such as Fret analysis module and 3D microstructure multi-level analysis module

XYZ orthogonal view provides multidimensional sectional views of samples with different thicknesses of xy, xz, and yz

Flexibly and quickly start your various experiments

Compatible with a range of fixed or live cell experimental applications

The configuration of the live cell culture room can meet the environmental conditions required for live cell culture (temperature, carbon dioxide) for long-term online observation of live cells

Live cell online dynamic observation helps researchers better and faster understand cell behavior and subcellular dynamics information

Can integrate with PerkinElmer automation platform to provide unmanned fully automated screening solutions

Experimental List

The Operetta High Content System can help you quickly conduct a series of experiments:

apoptosis

cell cycle

cell differentiation

cell migration

cell proliferation

Quantification of cellular morphological changes

Cytoskeleton rearrangement

毒性研究

In situ fluorescence hybridization (FISH)

Lipid droplet analysis

Neural growth

protein expression

Receptor activation

RNAi screening

Signal pathway analysis

transcription factor

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免责声明: For research use only. Not for use in diagnostic procedures.

Specifications